A whiff of hope: smell test detects Covid-19 early warning

The whole world has felt ambushed by COVID-19, but it’s only recently that experts have realised that the sense of smell is one of the first things to be attacked – well before any other symptoms present themselves. Now, IFF (International Flavors & Fragrance) have helped develop a smell-test to take at home, donating scents from their living technology collection to aid the testing process…

Scientists now agree that the loss of smell represents an early warning sign of Coronavirus. Anosmia (smell loss) and dysgeusia (taste loss) are extremely common symptoms that may appear before any other symptoms to suspect a patient might be infected. Researchers developing the pioneering (and self-administered) test say that ‘early awareness of exposure may trigger testing sooner and improve the overall accuracy of testing for COVID-19.’ And as we now know – the earlier a possible infection can be detected and the patient made aware, the fewer other members of the public could be infected.

‘IFF has a long history of developing innovative solutions for a multitude of global challenges,’ commented Dr. Gregory Yep, IFF’s Chief Scientific and Sustaina­bility Officer. ‘Our ongoing collaboration with Dr. Albers underscores our commitment to do more good for people and planet, and I hope our donation can help contribute to a solution for this pandemic.’

The Blavatnik Sensory Disorders Fund at Harvard Medical School is enabling the building of apps that allow long-distance symptom tracking and smell testing from home, and up to 400 patients at MGH, Brigham and Women’s Hospital and the Spaulding Rehabiliation Hospital will be participating in their first round of testing.

After receiving a small and simple to use scratch card, the test will then be conducted on a patient’s own phone app (or via a tablet, or computer.) During the test, participants will answer a series of questions about possible COVID-19 symptoms and loss of smell and/or taste. By distributing this free smell test, the hopes are that presymptomatic detection of anosmia will trigger full testing and prompt patients to self-isolate – even if no other symptoms are present.

With the recent lowering of social distancing measures, many experts fear a second (and possibly even larger) spike in the numbers of new COVID-19 infections, it behoves us to be extra cautious and to be forewarned, as they say, is forearmed.

Dr. Mark Albers, an MGH neurologist specialising in memory and olfactory disorders, was one of the leading experts who wanted to set up the test, explaining that, ‘There is so much we don’t know about COVID-19, but the research shows that loss of smell and taste play a prominent role in identifying possible patients with the virus,’

‘If we can provide reliable self-administered tests to people and health care workers,’ Dr. Albers continued, ‘we may be able to slow the spread of the disease in the future and chart recovery of smell function, which may be helpful to determine when it is safe to reengage after having the COVID infection.’

Fascinating, isn’t it, how we are only now discovering how many medical conditions have early warning signs reflected in a loss of smell? Perhaps now, those scientists who were toiling away studying the sense of smell – which for so many years was disregarded as insignificant – will be taken more seriously; and (we hope – perhaps naively) will be given the funding they so desperately need.

By Suzy Nightingale

AbScent – Lost your sense of smell? They can help…

Chrissi Kelly lost her sense of smell in 2012. She had no idea how seriously this would impact on her life – and how many people struggle with this on a daily basis. Since then, she’s launched AbScent and devoted her life to finding out more about the loss of smell, and developed Snif: a smell training app that’s a personal coach to re-building or enhancing the sense of smell…

Since the devastating loss of smell caused by a virus, Chrissi Kelly has been busy founding the charity AbScent, and supporting thousands of other people with smell loss through smell training. Having taken courses with Professor Thomas Hummel, the author of the first research paper on smell training at the University of Dresden, Germany; Chrissi used his tried and trusted techniques alongside specially devised ‘smell training kits’, which have significantly helped people to reconnect with their recovering sense of smell. Chrissi also speaks at conferences, runs workshops, online events and private sessions to support people with the condition. She’s a busy woman, indeed, and we were thrilled to join her at Jo Malone London‘s flagship Regent Street Store, recently, where they were kindly playing host to the official launch of AbScent.

 

 

Chrissi explained ‘the three pillars of smell training’ approach AbScent use to aid those with a loss of smell – be that from a head injury, illness, medication or even those who were born with what they perceive as no sense of smell at all. The message is, there is help out there, and there are active ways you can learn more, connect with others and improve your sense of smell with time.

Step 1:Find out where your sense of smell is today. Use the AbScent self-assessment form, here. You won’t know if you are improving if you don’t know where you’ve started.’

Step 2: Smell Train. There are full instructions for making your own Smell Training Kit, here. Or, if you prefer, you can purchase a pre-assembled Smell Training Kit.

Step 3: Take note of your experiences. AbScent provide a guide for keeping notes and a downloadable diary.

You can also now use the online Snif App – to ‘guide and instruct users so that each smell training session is consistent and productive. Snif becomes a personal coach that takes the guesswork out of practicing, presenting a mindful and focussed way of tracking your development. Currently web-based, a native app is in the works.

 

 

Think of it as physiotherapy for your nose,’ AbScent explain. ‘The brain can rewire itself, but this is a slow process. Smell training is a commitment and it takes time. You will need to train for a minimum of four months, twice a day.’ That may seem like quite an undertaking, but when you realise how earth-shattering a loss of smell can be, it’s definitely worthwhile. ‘I’d say that pretty much everyone who has suffered loss of smell goes on to develop depression in varying forms,’ Chrissi told us.

Imagine not being able to smell your own child, your partner – yourself. Or wondering is a phantom burning smell is actually your house burning down – a loss of smell isn’t simply not being able to smell things as well/at all: it can come with a whole host of disturbing side-effects, such as all food and drink suddenly tasting foul (leading to eating disorders or malnutrition).

It can feel incredibly difficult to go to your doctor if you’re not sure how to describe your symptoms, or what they need to know. Be assured that the medical profession are now – thank goodness – taking smell loss seriously. And AbScent have made a guide to talking to your doctor, so you know exactly what to say. They even have a list of clinics to go for further help.

 

 

AbScent have also launched a Sense of Smell Project. ‘We are trying to learn more about what it is like to live with this condition and how people’s lives change as a result.’ By taking part in their survey and telling your story, you can help them get a clear overview of subjects that may have not been considered, in order to ‘develop healing strategies and better ways to support patients.’

We cannot applaud enough, the work that Chrissi and her AbScent team have done so far, and their aims of helping even more people who may well have been ignored – or not even taken their own loss of smell seriously – for so long. We also hope that other fragrance houses will join in the support. Smell loss can strike any one of us at any time, and if we all work together, what a world of sensorial discoveries we could uncover…

By Suzy Nightingale

IFRA's Fragrance Forum put our sense of smell on the map…

Every year, IFRA – the trade association promoting the safe creation, development and enjoyment of fragrance) organise a Fragrance Forum – an utterly fascinating coming together of highly engaging speakers with experts from just about every sector you can imagine – all of whom are linked by their expertise and interest in the sense of smell. We were thrilled to be invited along for their seventh Forum as part of the fragrance press, and so found ourselves learning the power of Medical Detection Dogs, how to make a Mosquito Invisibility Cape, how to smell-map a city, how the Pre-Raphaelites responded to the stench of the river Thames (by linking it to paintings of fallen women, it turns out), the difference between Synaesthesia (one of my favourite subjects ever) and cross-modal correspondences, and font-sniffing (as in: can you smell/taste/hear typefaces? Short story: yes.)
To give you a taste of the breadth and diversity of the subjects covered, here’s a little more about the speakers and the topics they spoke about so passionately. In a Fragrance Forum for which the theme was Scents & Sensibility (a nod to this year marking the 200th anniversary of Jane Austen’s death), we left with a renewed excitement of the sense that some neglect, but which many of us have built our careers and, indeed, our lives around…
Dr Claire Guest – Sniffing it out
CEO Medical Detection Dogs
Claire has been involved in the training of dogs for tasks involving scent for over twenty years. Since 2002 she has been professionally involved in training dogs in the detection of human disease through scent. She is now the CEO of Medical Detection Dogs (MDD) the leading charity training dogs, pioneering both medical assistance and disease detection, and is not only a pioneer of the training but committed to carrying out empirical research to improve operations and to inform future medical technologies.

Professor James Logan How to make a mosquito invisibility cloak
London School of Hygiene and Tropical Medicine
James has more than 10 years of experience in the laboratory and field – in the UK and overseas – of controlling insects of medical and veterinary importance. He has an award-winning PhD investigating why some people are bitten more than others by mosquitoes and midges. Mosquito-borne diseases affect more than half the world’s population, diseases transmitted by insects account for more than 17% of all infectious diseases, causing more than one million deaths. By understanding more about mosquitoes and their incredible sense of smell, we can develop better ways to control one of the world’s most formidable forces. One day, we may even be able to make ourselves completely invisible.

Key theme: Scent and our surroundings
Kate McLean – Programme Director for Graphic Design at Canterbury Christ Church University
Dr Daniele Quercia – Bell Labs, Cambridge
On the Impossibility of Mapping the Smellscape
Kate McLean is a British artist and designer and mapper of urban smellscapes – the term used to describe the odour landscape around us. She runs smellscape mapping workshops, leads smellwalks around the world and has co-edited a book, Designing with Smell: Practices, Techniques and Challenges (2017). Her talk looked at how interative design research can be used to investigate how the general public perceives and reacts to smells in public spaces.
Daniele Quercia leads the Social Dynamics group at Bell Labs in Cambridge. He has been named one of Fortune magazine’s 2014 Data All-Stars, and spoke about “happy maps” at TED. His research has been focusing in the area of urban informatics, focussing on the fact that, although humans are able to potentially discriminate thousands of different odours, smell is simply hard to measure. SmellyMaps have recently proposed a new way of capturing the entire urban smellscape from social media data (i.e., tags on Flickr pictures or tweets). The SmellyMaps project aims at disrupting the mainly negative view of city odours and being able to celebrate the complex smells of our cities.

Dr Christina Bradstreet – Art, Smell and Sanitation
The National Gallery
Christina is Courses and Events Programmer at the National Gallery and she has taught 19th-century painting at Birkbeck College as well as guest lectures at Sotheby’s Institute, Royal Holloway College and the Courtauld Institute. So, how did the Pre-Raphaelites respond to the stench of the River Thames, in the summer of 1858? This talk explored how the urban stink influenced artists in Britain and beyond in the nineteenth-century.

Key theme: Scent and psychology
Dr Clare Jonas – Synaesthesia – a blending of the senses
University of East London
Synaesthesia is a fascinating condition in which the senses become entangled so that music might appear to have shapes, or smells have colours. In this talk Clare explored what synaesthesia is and how it relates to mechanisms of multisensory perception in the general population. She also explored visual aspects of art, advertising and packaging and how psychological research links them to taste and smell.

Sarah Hyndman – Wake up and smell the fonts!
Founder and Director, Type Tasting
Type Tasting founder Sarah Hyndman is a graphic designer, author and public speaker, known for her interest in the psychology of type. Her main area of expertise is multi sensory typography, she works on collaborative research studies with the Crossmodal Research Laboratory at the University of Oxford. In her talk Sarah explored how visual language influences all of our senses as it tells the story of a product. The visual translation of luxury, gender or smell creates anticipation, informs our choices and enhances our experiences.
Innovative new research into crossmodal perception is now mapping the typography of smell – understanding this enables us to use visual language to accentuate nuances and nudge behaviour… just one of the many subjects we left wanting to explore in more depth, so stay tuned for our further investigations!
Written by Suzy Nightingale